Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927927 | 0.92 | HASPIN (0.58) | ROCK2ROCK1EGFRHDAC6HDAC2 | |
| SCHEMBL4483467 | 0.89 | MMP13 (0.59) | ROCK2ROCK1EGFRNR1H4HPGD | |
| SCHEMBL2924662 | 0.87 | HDAC6 (0.74) | ROCK2ROCK1EGFRHDAC6HDAC2 | |
| SCHEMBL18063672 | 0.86 | ALDH1A1 (0.56) | ROCK2ROCK1EGFRHDAC6HDAC2 | |
| SCHEMBL11901042 | 0.85 | HDAC6 (0.70) | HDAC6HDAC2HDAC8ERCC1ERCC4 | |
| SCHEMBL24628486 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1EGFRHDAC6HDAC2 | |
| SCHEMBL26816033 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1EGFRHDAC6HDAC2 | |
| SCHEMBL24628975 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1EGFRHDAC1 | |
| SCHEMBL4495476 | 0.85 | MLYCD (0.80) | ROCK2NR1H4MLYCDHPGDLMNA | |
| SCHEMBL254400 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542972-B1 | HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS | DOW CHEMICAL CO (US) | 1997-11-05 | — | — | EP | claimed |
| US-5134218-A | Hydroxy-functional poly(amide ethers) as thermoplastic barrier resins | THE DOW CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | claimed |
| US-20100168377-A1 | Catalytic conversion of amide compounds to methyl ether polymers and methyl ether ladder polymers | CARTER TECHNOLOGIES (US) | 2010-07-01 | — | — | US | disclosed |
| US-20080114150-A1 | Catalytic conversion of carbonyl type compounds, including amides and others, to methyl ether polymers, substituted methyl ether polymers and methyl ether ladder polymers | CARTER TECHNOLOGIES (US) | 2008-05-15 | — | — | US | disclosed |
| EP-0542972-B1 | HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS | DOW CHEMICAL CO (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0542972-A1 | HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS | THE DOW CHEMICAL COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992021707-A1 | HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS | THE DOW CHEMICAL COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5143998-A | HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS | THE DOW CHEMICAL COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5143998-A | HYDROXY-FUNCTIONAL POLY(AMIDE ETHERS) AS THERMOPLASTIC BARRIER RESINS | THE DOW CHEMICAL COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5134218-A | Hydroxy-functional poly(amide ethers) as thermoplastic barrier resins | THE DOW CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | disclosed |