Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110335 | 0.84 | KDM4E (0.39) | TLR7CYP2D6KDM4E | |
| SCHEMBL6777793 | 0.84 | PKM (0.35) | TLR7BRD4 | |
| SCHEMBL6777224 | 0.84 | EPHX1 (0.37) | TLR7MAPTKDM4EDRD2DRD3 | |
| SCHEMBL6783545 | 0.83 | PPID (0.40) | TLR7KDM4E | |
| Hydrochloric Acid SCHEMBL6110768 | 0.83 | KDM4E (0.38) | TLR7CYP2D6KDM4E | |
| SCHEMBL6283619 | 0.81 | TLR7 (0.32) | TLR7 | |
| SCHEMBL6096758 | 0.81 | MEN1 (0.42) | TLR7SMN1; SMN2MAPTBRD4KDM4E | |
| SCHEMBL6776784 | 0.80 | ALDH1A1 (0.48) | TLR7SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL6284008 | 0.79 | TLR7 (0.33) | TLR7MAPT | |
| SCHEMBL6782629 | 0.79 | EPHX1 (0.42) | RAB9ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |