Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773686 | 0.87 | TLR7 (0.31) | TLR7 | |
| SCHEMBL6783545 | 0.83 | PPID (0.40) | TLR7ALDH1A1LMNA | |
| SCHEMBL6777224 | 0.81 | EPHX1 (0.37) | TLR7MAPTALDH1A1 | |
| SCHEMBL6110335 | 0.80 | KDM4E (0.39) | TLR7ALDH1A1 | |
| SCHEMBL6780666 | 0.79 | TLR7 (0.37) | TLR7MAPT | |
| SCHEMBL6777793 | 0.79 | PKM (0.35) | TLR7 | |
| Hydrochloric Acid SCHEMBL6110768 | 0.79 | KDM4E (0.38) | TLR7ALDH1A1 | |
| SCHEMBL6781809 | 0.78 | POLB (0.42) | TLR7MAPTALDH1A1 | |
| SCHEMBL6776784 | 0.78 | ALDH1A1 (0.48) | TLR7ALDH1A1LMNA | |
| SCHEMBL6774657 | 0.78 | MAPT (0.49) | TLR7MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903113-B2 | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-20040157879-A1 | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157879-A1 | Urea substituted imidazopyridines | EIF2AK2, UMPS, IRF3 | TLR7 269/4885MAPT 2103/4885ALDH1A1 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.