Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787497 | 0.81 | ADAM17 (0.44) | ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL6785475 | 0.80 | KIF11 (0.38) | KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL6785281 | 0.76 | ESR2 (0.40) | GAAESR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6786095 | 0.73 | ESR1 (0.39) | ESR1ALDH1A1LMNA | |
| SCHEMBL6786562 | 0.70 | HSP90AA1 (0.40) | KMT2AMEN1GAAESR1ALDH1A1 | |
| SCHEMBL6784818 | 0.70 | ESR1 (0.42) | KMT2AMEN1GAAESR1ALDH1A1 | |
| SCHEMBL6785959 | 0.69 | KIF11 (0.39) | ESR1 | |
| SCHEMBL10740520 | 0.69 | MEN1 (0.46) | KMT2AMEN1ATMGAAESR1 | |
| SCHEMBL6671068 | 0.67 | KMT2A (0.44) | KMT2AMEN1ATMGAAALDH1A1 | |
| SCHEMBL17102000 | 0.66 | KMT2A (0.49) | KMT2AMEN1ATMGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825354-B2 | OSTEOPOROSIS; RHEUMATIC DISEASES | WYETH HOLDINGS CORPORATION | 2004-11-30 | — | — | US | disclosed |