Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786095 | 0.83 | ESR1 (0.39) | ESR2KCNK2ALDH1A1LMNAKIF11 | |
| SCHEMBL6784818 | 0.83 | ESR1 (0.42) | ESR2GAAMAPTKCNK2ALDH1A1 | |
| SCHEMBL6786562 | 0.83 | HSP90AA1 (0.40) | ESR2GAAMAPTKCNK2ALDH1A1 | |
| SCHEMBL6782624 | 0.82 | ADAM17 (0.49) | PKMALDH1A1LMNATDP1 | |
| SCHEMBL6782872 | 0.76 | KMT2A (0.40) | GAAMAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL6782115 | 0.75 | FFAR1 (0.37) | LTA4H | |
| SCHEMBL6785959 | 0.74 | KIF11 (0.39) | ESR2PKMCTBP2KIF11ESR1 | |
| SCHEMBL6785653 | 0.71 | ADAM17 (0.49) | — | |
| SCHEMBL3173618 | 0.71 | ESR2 (0.55) | ESR2LTA4HCALM1GAAPKM | |
| SCHEMBL8760915 | 0.71 | ESR1 (0.73) | ESR2LTA4HCALM1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825354-B2 | OSTEOPOROSIS; RHEUMATIC DISEASES | WYETH HOLDINGS CORPORATION | 2004-11-30 | — | — | US | disclosed |