Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.77 |
| ▸ | HPGD | P15428 | 7/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.77 |
| ▸ | POLB | P06746 | 3/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.77 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | CLK2 | P49760 | 1/20 | 0.77 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10914782 | 0.99 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL10654073 | 0.94 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL29593740 | 0.92 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL6783172 | 0.92 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL8435331 | 0.91 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL9626969 | 0.90 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL3957125 | 0.90 | ALDH1A1 (0.79) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL9792010 | 0.90 | KCNH2 (0.79) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL965845 | 0.90 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL10695169 | 0.90 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571812-A | TREATMENT OF INFECTIONS OF GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | claimed |
| US-5969141-A | Intermediates for 7-amino-1-cyclopropyl-6,8-dihalogeno-1,4-dihydro-4-oxo-3-quinolinecarbox ylic acid antibacterial agents | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-19 | — | — | US | disclosed |
| US-5777181-A | 2, 4, 5-trihalogeno- and 2, 3, 4, 5-tetrahalogenobenzene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5571812-A | TREATMENT OF INFECTIONS OF GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |
| US-5565614-A | FLUORINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| US-5530158-A | CHEMICAL INTERMEDIATE FOR ANTIBACTERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5468861-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| US-5362909-A | Two stage fluorination | BAYER AKTIENGESELLSCHAFT (DE) | 1994-11-08 | — | — | US | disclosed |
| US-5200548-A | Intermediates for bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-06 | — | — | US | disclosed |
| US-5072038-A | Chemical intermediates for bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| US-4895803-A | QUINOLINE-OR NAPHTHAPYRIDINE/1,8-/ DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| EP-0191390-B1 | 1-Cyclopropyl-1,4-dihydro-4-oxo-7-[4-(oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl]-quinoline-3-carboxylic acids, process for their preparation and bactericides containing them | BAYER AG (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4703047-A | 1-Cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-quinolinecarboxylic acid antibacterial agents | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-27 | — | — | US | disclosed |
| EP-0191390-A1 | 1-Cyclopropyl-1,4-dihydro-4-oxo-7-[4-(oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl]-quinoline-3-carboxylic acids, process for their preparation and bactericides containing them | BAYER AG (DE) | 1986-08-20 | — | — | EP | disclosed |
| EP-0178388-A1 | Quinolinecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-23 | — | — | EP | disclosed |