Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 3/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784267 | 1.00 | NQO2 (0.49) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL27833892 | 0.92 | NPC1 (0.50) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL28264296 | 0.92 | ABAT (0.52) | NQO2MEN1KMT2ALMNACA2 | |
| SCHEMBL27762421 | 0.92 | NPC1 (0.50) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL28263236 | 0.91 | LMNA (0.45) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL27565138 | 0.91 | FNTA (0.42) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL28263238 | 0.87 | MAPT (0.49) | NQO2MEN1KMT2AESR2NPC1 | |
| SCHEMBL28271291 | 0.87 | ESR1 (0.44) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL11870822 | 0.83 | SRD5A2 (0.40) | NQO2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11870828 | 0.83 | SRD5A2 (0.40) | NQO2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-10918609-B2 | Pharmaceutical composition for preventing or treating arthritis or inflammatory disease containing 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol as active ingredient | CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2021-02-16 | — | — | US | disclosed |
| WO-2020206424-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| US-20190175521-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ARTHRITIS OR INFLAMMATORY DISEASE CONTAINING 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROPYL-1-EN-1-YL)PHENOL AS ACTIVE INGREDIENT | CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2019-06-13 | — | — | US | disclosed |
| US-10265276-B2 | Pharmaceutical composition for preventing or treating arthritis or inflammatory disease containing 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol as active ingredient | CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2019-04-23 | — | — | US | disclosed |
| US-10125073-B2 | 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol and preparation method therefor | CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-11-13 | — | — | US | disclosed |
| US-20180133169-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ARTHRITIS OR INFLAMMATORY DISEASE CONTAINING 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROPYL-1-EN-1-YL)PHENOL AS ACTIVE INGREDIENT | Chungbuk National University Industry-Academic Coo peration Foundation (KR) | 2018-05-17 | — | — | US | disclosed |
| US-20180044275-A1 | 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROP-1-EN-1-YL)PHENOL AND PREPARATION METHOD THEREFOR | CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-02-15 | — | — | US | disclosed |
| CN-107438433-A | Pharmaceutical composition for preventing and treating arthritis or inflammatory diseases containing 2-methoxy-4- (3- (4-methoxyphenyl) prop-1-en-1-yl) phenol as an active ingredient | 忠北大学校产学协力团 | 2017-12-05 | — | — | CN | disclosed |
| CN-107428647-A | 2 methoxyl groups 4 (3 (4 methoxyphenyls) the third 1 base of alkene 1) phenol and preparation method thereof | 忠北大学校产学协力团 | 2017-12-01 | — | — | CN | disclosed |
| WO-2016144042-A1 | 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROP-1-EN-1-YL)PHENOL AND PREPARATION METHOD THEREFOR | 충북대학교 산학협력단 | 2016-09-15 | — | — | WO | disclosed |
| US-6803367-B2 | ANTICANCER AGENTS; SYNERGISTIC MIXTURES | TAKARA SHUZO CO., LTD. (JP) | 2004-10-12 | — | — | US | disclosed |
| US-20030065014-A1 | Substance for inducing apoptosis | TAKARA BIO INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6525082-B1 | 2-hydroxy-4-(1-imidazolyl)-2-cyclopenten-1-one; inhibiting growth of cancer cells | TAKARA SHUZO CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| EP-1048641-A1 | APOPTOSIS INDUCER | Takara Shuzo Co, Ltd. (JP) | 2000-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044275-A1 | 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROP-1-EN-1-YL)PHENOL AND PREPARATION METHOD THEREFOR | STAT3, RELA, NFKBIA | NQO2 2908/4885MEN1 2277/4885KMT2A 1404/4885 |
| US-20030065014-A1 | Substance for inducing apoptosis | BAX, BCL2, BAD | NQO2 2200/4885MEN1 3606/4885KMT2A 4360/4885 |
| US-20180133169-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ARTHRITIS OR INFLAMMATORY DISEASE CONTAINING 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROPYL-1-EN-1-YL)PHENOL AS ACTIVE INGREDIENT | TYR, COL2A1, SYVN1 | NQO2 3091/4885MEN1 2907/4885KMT2A 1344/4885 |
| US-20190175521-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ARTHRITIS OR INFLAMMATORY DISEASE CONTAINING 2-METHOXY-4-(3-(4-METHOXYPHENYL)PROPYL-1-EN-1-YL)PHENOL AS ACTIVE INGREDIENT | TYR, COL2A1, SYVN1 | NQO2 3091/4885MEN1 2907/4885KMT2A 1344/4885 |
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | NQO2 1158/4885MEN1 3280/4885KMT2A 737/4885 |
| US-10918609-B2 | Pharmaceutical composition for preventing or treating arthritis or inflammatory disease containing 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol as active ingredient | TYR, COL2A1, SYVN1 | NQO2 3091/4885MEN1 2907/4885KMT2A 1344/4885 |
| US-10125073-B2 | 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol and preparation method therefor | STAT3, RELA, NFKBIA | NQO2 2908/4885MEN1 2277/4885KMT2A 1404/4885 |
| US-10265276-B2 | Pharmaceutical composition for preventing or treating arthritis or inflammatory disease containing 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol as active ingredient | TYR, COL2A1, SYVN1 | NQO2 3091/4885MEN1 2907/4885KMT2A 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.