Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780800 | 0.79 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6784772 | 0.79 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6779969 | 0.78 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6780763 | 0.76 | LMNA (0.43) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6781233 | 0.73 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6780798 | 0.73 | KDM4E (0.48) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6779130 | 0.72 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6780419 | 0.72 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6781915 | 0.71 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL11871051 | 0.70 | LMNA (0.68) | EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706705-B1 | SLOW AND CONTINUOUS BLOOD PRESSURE REDUCING ACTION AND IS USEFUL AS AN ANTIHYPERTENSIVE AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-0794178-A1 | QUINAZOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |