Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784767 | 0.79 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6779978 | 0.78 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL11871051 | 0.69 | LMNA (0.68) | — | |
| SCHEMBL6780798 | 0.68 | KDM4E (0.48) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL13941828 | 0.68 | LMNA (0.68) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6780800 | 0.67 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL26038211 | 0.66 | LMNA (0.48) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6781233 | 0.65 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6780763 | 0.64 | LMNA (0.43) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL14292897 | 0.63 | LMNA (0.63) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706705-B1 | SLOW AND CONTINUOUS BLOOD PRESSURE REDUCING ACTION AND IS USEFUL AS AN ANTIHYPERTENSIVE AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-0794178-A1 | QUINAZOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |