Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779429 | 0.74 | GLA (0.54) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6784767 | 0.73 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL5462447 | 0.71 | ADRA1D (0.73) | ADRA1DADRA1AADRA1B | |
| SCHEMBL15887987 | 0.70 | KDM4E (0.62) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14473121 | 0.70 | KDM4E (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL11871051 | 0.70 | LMNA (0.68) | GLAGAALMNA | |
| SCHEMBL6781233 | 0.70 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL13941828 | 0.69 | LMNA (0.68) | GLAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL6781777 | 0.69 | TP53 (0.50) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6784772 | 0.68 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706705-B1 | SLOW AND CONTINUOUS BLOOD PRESSURE REDUCING ACTION AND IS USEFUL AS AN ANTIHYPERTENSIVE AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-0794178-A1 | QUINAZOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |