SCHEMBL6785186

SCHEMBL6785186

CCCCC(S)[Si](OCC)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.32
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032972 0.93 OPRM1 (0.39) DNM1OPRM1
SCHEMBL2981412 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL11784858 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL29249880 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL11784332 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL2983365 0.91 OPRM1 (0.38) DNM1OPRM1
SCHEMBL6791777 0.86
SCHEMBL6785262 0.79 DNM1 (0.33) DNM1
SCHEMBL383092 0.79
SCHEMBL333790 0.77 CA2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed
US-20040259992-A1 Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses 3M ESPE AG (DE) 2004-12-23 US disclosed
EP-1360245-B1 ADHESIVES FOR METAL-POLYMER COMPOSITES 3M ESPE AG (DE) 2004-07-14 EP disclosed
EP-1360245-A1 ADHESIVES FOR METAL-POLYMER COMPOSITES 3M Espe AG (DE) 2003-11-12 EP disclosed
WO-2002072711-A1 ADHESIVES FOR METAL-POLYMER COMPOSITES 3M ESPE AG (DE) 2002-09-19 WO disclosed
US-4622412-A Process for preparation of mercapto silicone fluid GENESEE POLYMERS CORPORATION, A CORP. OF MI 1986-11-11 US disclosed
US-4612055-A Stabilized blends of thiofunctional polysiloxane fluids and organopolysiloxane fluids and a process for stabilizing the same SWS SILICONES CORPORATION (US) 1986-09-16 US disclosed
US-4588771-A Stabilized thiofunctional polysiloxane fluids and a process for stabilizing the same SWS SILICONES CORPORATION (US) 1986-05-13 US disclosed
US-4289867-A Organofunctional polysiloxane polymers and a method for preparing the same SWS SILICONES CORPORATION (US) 1981-09-15 US disclosed
US-4251277-A CORROSION INHIBITORS, RELEASE AGENTS SWS SILICONES CORPORATION (US) 1981-02-17 US disclosed
US-4230816-A Thiofunctional polysiloxane polymers SWS SILICONES CORPORATION (US) 1980-10-28 US disclosed
US-4046795-A Process for preparing thiofunctional polysiloxane polymers SWS SILICONES CORPORATION (US) 1977-09-06 US disclosed
US-3997581-A BONDING AGENTS IN SULFUR VULCANIZABLE RUBBERS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259992-A1 Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses ITGA2, ITGB2, ITGA2B DNM1 4267/4885OPRM1 435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.