Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784474 | 0.88 | MTNR1A (0.44) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6787623 | 0.86 | CYP2D6 (0.46) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL27660942 | 0.81 | NQO2 (0.40) | NQO2 | |
| SCHEMBL27309736 | 0.79 | CTSS (0.42) | NQO2 | |
| SCHEMBL7217624 | 0.78 | NQO2 (0.41) | NQO2 | |
| SCHEMBL28736190 | 0.75 | NR1H4 (0.45) | NQO2 | |
| SCHEMBL27433809 | 0.75 | NQO2 (0.39) | NQO2 | |
| SCHEMBL27983901 | 0.74 | POLB (0.40) | NQO2 | |
| SCHEMBL6786984 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL23218723 | 0.74 | NLRP3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737431-B2 | SUCH AS N-(3-(2-METHYLBENZOXAZOL-7-YL)PROPYL)PROPANAMIDE; CIRCADIAN RHYTHM RELATED DISORDERS | BRISTOL-MYERS SQUIBB COMPANY | 2004-05-18 | — | — | US | disclosed |
| US-20030216456-A1 | Benzoxazole derivatives as novel melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216456-A1 | Benzoxazole derivatives as novel melatonergic agents | MTNR1A, MTNR1B, MC1R | MTNR1A 1/4885MTNR1B 2/4885NQO2 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.