Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906421 | 0.81 | KDM1A (0.58) | NPC1RAB9APKMSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6883145 | 0.80 | KDM1A (0.56) | NPC1RAB9APKMSMN1; SMN2KMT2A | |
| SCHEMBL6797100 | 0.79 | KMT2A (0.46) | NPC1RAB9APKMSMN1; SMN2KMT2A | |
| SCHEMBL6801290 | 0.72 | MAPT (0.51) | NPC1RAB9APKMSMN1; SMN2KMT2A | |
| SCHEMBL11703495 | 0.71 | HTR3A (0.52) | RAB9ASMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL8390746 | 0.68 | GPR3 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27517531 | 0.66 | SLC2A1 (0.59) | NPC1RAB9APKMSMN1; SMN2KMT2A | |
| SCHEMBL4911184 | 0.66 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4909622 | 0.65 | KDM1A (0.73) | NPC1RAB9APKMSMN1; SMN2KMT2A | |
| SCHEMBL11052646 | 0.65 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2KMT2ALMNABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821983-B2 | INHIBITORS OF TOPOISOMERASE II CAN EXHIBIT ANTITUMOR ACTIVITY | ACADEMIA SINICA (TW) | 2004-11-23 | — | — | US | disclosed |
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | ACADEMIA SINICA (TW) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | DPP9, NANP, NAT1 | NPC1 283/4885RAB9A 100/4885PKM 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.