Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791960 | 0.82 | KMT2A (0.63) | MAPTALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6797100 | 0.78 | KMT2A (0.46) | MAPTALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL38659285 | 0.73 | MEN1 (0.68) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6786741 | 0.72 | NPC1 (0.46) | MAPTKMT2ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL7162207 | 0.70 | PTGS2 (0.56) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11501387 | 0.69 | ALDH1A1 (0.45) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL26023168 | 0.68 | ALDH1A1 (0.57) | MAPTALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL27801296 | 0.66 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11843531 | 0.66 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL13313368 | 0.66 | KLK3 (0.56) | MAPTALDH1A1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821983-B2 | INHIBITORS OF TOPOISOMERASE II CAN EXHIBIT ANTITUMOR ACTIVITY | ACADEMIA SINICA (TW) | 2004-11-23 | — | — | US | disclosed |
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | ACADEMIA SINICA (TW) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | DPP9, NANP, NAT1 | MAPT 918/4885ALDH1A1 224/4885KMT2A 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.