SCHEMBL67874

SCHEMBL67874

Oc1cc(F)c(O)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
SELE P16581 1/20 0.35
ERN1 O75460 1/20 0.34
ADRB2 P07550 2/20 0.33
CYP3A4 P08684 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
ADRA1A P35348 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
APEX1 P27695 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5949073 0.83 IDO1 (0.32) CA3CA6CA5ACA9CA14
SCHEMBL30367972 0.79 CA1 (0.40) CA3CA6CA5ACA9CA14
SCHEMBL258682 0.79 CES2 (0.38) CA3CA6CA5ACA9CA14
SCHEMBL5509678 0.79 CES2 (0.38) CA3CA6CA5ACA9CA14
SCHEMBL29716720 0.79 CES2 (0.38) CA3CA6CA5ACA9CA14
SCHEMBL2396959 0.79 CA1 (0.40) CA3CA6CA5ACA9CA14
SCHEMBL516135 0.78 ERN1 (0.39) CA3CA6CA5ACA9CA14
SCHEMBL515819 0.77 CES2 (0.36) CA3CA6CA5ACA9CA14
SCHEMBL5948999 0.77 ERN1 (0.34) CA3CA6CA5ACA9CA14
SCHEMBL368571 0.77 CES2 (0.36) CA3CA6CA5ACA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
EP-2935695-B1 ELECTRICAL INSULATION PAPER, METHODS OF MANUFACTURE, AND ARTICLES MANUFACTURED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-04 EP disclosed
CN-109790189-A The reactive mesogen coughed up based on dibenzo [D, B] thiophene 洛马克斯有限公司 2019-05-21 CN disclosed
US-20180162086-A1 HONEYCOMB PAPER SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-06-14 US disclosed
EP-3302956-A1 HONEYCOMB PAPER SABIC Global Technologies B.V. (NL) 2018-04-11 EP disclosed
EP-2831324-B1 ELECTRICAL INSULATION PAPER, METHODS OF MANUFACTURE, AND ARTICLES MANUFACTURED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-09-20 EP disclosed
EP-2831322-B1 HONEYCOMB PAPER SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-08-02 EP disclosed
US-20170030020-A1 ELECTRICAL INSULATION PAPER, METHODS OF MANUFACTURE, AND ARTICLES MANUFACTURED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-02-02 US disclosed
EP-2831326-B1 ELECTRICAL INSULATION PAPER, METHODS OF MANUFACTURE, AND ARTICLES MANUFACTURED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-10-19 EP disclosed
CN-105713388-A FLAME RETARDANT POLYIMIDE/POLYESTER-POLYCARBONATE COMPOSITIONS 沙特基础全球技术有限公司 2016-06-29 CN disclosed
WO-2008063724-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO disclosed
US-20080119618-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
US-20080119597-A1 Blend of an aromatic polyester, and an aromatic polycarbonate; transparent covers GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
US-20080119596-A1 Transparant blend of an aromatic polyester, and an aromatic polycarbonate; transparent covers GENERAL ELECTRIC COMPANY (US) 2008-05-22 US disclosed
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed
EP-0664014-B1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL NV (NL) 1998-08-19 EP disclosed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed
EP-0664014-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS Akzo Nobel N.V. (NL) 1995-07-26 EP disclosed
WO-1994008269-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed