Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715726 | 0.78 | NPC1 (0.44) | NPC1JAK2RAB9APAX8ICMT | |
| SCHEMBL5715943 | 0.78 | NPC1 (0.44) | NPC1JAK2RAB9APAX8ICMT | |
| SCHEMBL6791674 | 0.77 | NPC1 (0.34) | NPC1JAK2RAB9APAX8ICMT | |
| SCHEMBL6793642 | 0.72 | NR1H2 (0.43) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL6792131 | 0.68 | HDAC3 (0.33) | — | |
| SCHEMBL6791085 | 0.67 | NR1H2 (0.34) | EPHX2ICMT | |
| SCHEMBL6789626 | 0.67 | NPC1 (0.46) | NPC1JAK2RAB9APAX8ICMT | |
| SCHEMBL27533268 | 0.67 | NPC1 (0.46) | NPC1JAK2RAB9APAX8ICMT | |
| SCHEMBL5716192 | 0.67 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL7612249 | 0.67 | ESR1 (0.38) | NPC1JAK2RAB9APAX8ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6822057-B2 | OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG | EXXON MOBIL CHEMICAL PATENTS INC. | 2004-11-23 | — | — | US | disclosed |
| US-6489480-B2 | COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-12-03 | — | — | US | disclosed |
| US-20020115806-A1 | Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-08-22 | — | — | US | disclosed |
| US-20020111265-A1 | GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-08-15 | — | — | US | disclosed |