SCHEMBL6788946

SCHEMBL6788946

CCOC(=O)C(Cc1ccccn1)N(C(=O)OC(C)(C)C)c1ccc(N)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PTPRA P18433 1/20 0.35
CPB2 Q96IY4 1/20 0.34
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
HIF1A Q16665 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
KLKB1 P03952 1/20 0.34
CYP1A2 P05177 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
HDAC6 Q9UBN7 4/20 0.33
HDAC1 Q13547 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080596 0.89 PTPRA (0.42) MEN1KMT2ASMN1; SMN2PTPRAALDH1A1
SCHEMBL6795835 0.87 KMT2A (0.41) MEN1KMT2AALDH1A1CYP1A2MAPT
SCHEMBL7262061 0.78 LMNA (0.41) GAAMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL6794086 0.77 SMO (0.49) MAPT
SCHEMBL27625790 0.76 MMP8 (0.43) GAAALDH1A1L3MBTL1
SCHEMBL7924347 0.75 CYP1A2 (0.42) SMN1; SMN2KDM4ETRPM8CYP1A2TDP1
SCHEMBL6487391 0.73 KDM4E (0.41) MEN1KMT2AALDH1A1KDM4EHIF1A
SCHEMBL7240720 0.72 POLB (0.37) KMT2ACPB2ALDH1A1MAPT
SCHEMBL16586263 0.72 HDAC6 (0.44) GAAMEN1KMT2ASMN1; SMN2PTPRA
SCHEMBL15925036 0.69 PTPRA (0.48) GAAMEN1KMT2ASMN1; SMN2PTPRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed
CN-1478077-A Benzamide compounds as APO B secretion inhibitors ����ҩƷ��ҵ��ʽ���� 2004-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 GAA 977/4885MEN1 2426/4885KMT2A 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.