Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 7/20 | 1.00 |
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | GRK2 | P25098 | 1/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | QPCT | Q16769 | 1/20 | 0.65 |
| ▸ | AOC2 | O75106 | 3/20 | 0.64 |
| ▸ | VHL | P40337 | 1/20 | 0.59 |
| ▸ | ELOC | Q15369 | 1/20 | 0.59 |
| ▸ | ELOB | Q15370 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190157 | 0.82 | POLB (0.70) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL3943549 | 0.78 | QPCT (1.00) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL11984949 | 0.78 | POLB (0.64) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL69614 | 0.78 | CA2 (0.79) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL14210016 | 0.77 | POLB (0.62) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL7434598 | 0.77 | TBXAS1 (0.68) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL31716110 | 0.77 | POLB (0.62) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL9742754 | 0.77 | POLB (0.62) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL2472028 | 0.76 | NSD2 (0.61) | POLBNSD2GRK2CASP6CTDSP1 | |
| SCHEMBL11825850 | 0.75 | POLB (0.60) | POLBNSD2GRK2CASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172147-B1 | AMIDE DERIVATIVES OF 2-(P-AMINOBENZYL)-BUTYRIC ACID AND ESTERS THEREOF HAVING HYPOLIPIDEMIZING ACTIVITY | Medosan Industrie Biochimiche Riunite S.r.l. (IT) | 1992-06-03 | — | — | EP | claimed |
| EP-0172147-A2 | Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity | Medosan Industrie Biochimiche Riunite S.r.l. (IT) | 1986-02-19 | — | — | EP | claimed |
| EP-4695240-A2 | CYCLIC VINYL SULFONE WRN INHIBITORS | Nimbus Wadjet, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2025245472-A1 | COMPOUNDS AND RELATED METHODS USEFUL FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| WO-2024215923-A2 | CYCLIC VINYL SULFONE WRN INHIBITORS | NIMBUS WADJET, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| CN-100482647-C | Pyrazole derivatives useful as COX-I inhibitors | ASTELLAS PHARMACY CO LTD (JP) | 2009-04-29 | — | — | CN | disclosed |
| CN-1717393-A | Pyrazole derivatives as COX-1 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-01-04 | — | — | CN | disclosed |
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2004-01-29 | — | — | US | disclosed |
| EP-1345909-A1 | PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002048114-A1 | PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2002-06-20 | — | — | WO | disclosed |
| EP-0172147-B1 | AMIDE DERIVATIVES OF 2-(P-AMINOBENZYL)-BUTYRIC ACID AND ESTERS THEREOF HAVING HYPOLIPIDEMIZING ACTIVITY | Medosan Industrie Biochimiche Riunite S.r.l. (IT) | 1992-06-03 | — | — | EP | disclosed |
| EP-0177659-B1 | ESTER DERIVATIVES OF 7-(OMEGA-OXYALKYL) THEOPHYLLINE AND THEIR PHARMACEUTICAL ACTIVITY | Medosan Industrie Biochimiche Riunite S.p.A. (IT) | 1990-09-19 | — | — | EP | disclosed |
| US-4618612-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS | MEDOSAN INDUSTRIE BIOCHIMICHE RIUNITE S.P.A. (IT) | 1986-10-21 | — | — | US | disclosed |
| EP-0177659-A1 | Ester derivatives of 7-(omega-oxyalkyl) theophylline and their pharmaceutical activity | Medosan Industrie Biochimiche Riunite S.p.A. (IT) | 1986-04-16 | — | — | EP | disclosed |
| EP-0172147-A2 | Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity | Medosan Industrie Biochimiche Riunite S.r.l. (IT) | 1986-02-19 | — | — | EP | disclosed |
| US-4563477-A | Process for the preparation of alpha-(N-pyrrolyl)-derivative acids, the salts and esters thereof; alpha-(N-pyrrolyl)-phenylacetic acids, the esters thereof, pharmaceutical compositions containing them and therapeutical applications thereof | ANTIBIOTICOS, S.A. (ES) | 1986-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | DCK, CCNK, CDK2 | POLB 631/4885NSD2 1481/4885GRK2 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.