Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 1.00 |
| ▸ | NSD2 | O96028 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GRK2 | P25098 | 1/20 | 0.65 |
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.65 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434598 | 0.79 | TBXAS1 (0.68) | QPCTNSD2POLBGRK2CASP6 | |
| SCHEMBL6790414 | 0.78 | POLB (1.00) | QPCTNSD2POLBGRK2CASP6 | |
| SCHEMBL69614 | 0.76 | CA2 (0.79) | QPCTNSD2POLBGRK2CASP6 | |
| SCHEMBL2730326 | 0.75 | QPCT (0.60) | QPCTPOLBLMNAGAAALDH1A1 | |
| SCHEMBL1664108 | 0.74 | QPCT (0.58) | QPCTPOLBCA2LMNATSHR | |
| Hydrochloric Acid SCHEMBL25180348 | 0.73 | CA2 (0.75) | QPCTNSD2POLBGRK2CASP6 | |
| Hydrochloric Acid SCHEMBL6765874 | 0.73 | CA2 (0.75) | QPCTNSD2POLBGRK2CASP6 | |
| SCHEMBL24059106 | 0.72 | ITGB3 (0.58) | QPCTNSD2POLBGRK2CASP6 | |
| SCHEMBL9490844 | 0.72 | QPCT (0.56) | QPCTNSD2POLBGRK2CASP6 | |
| SCHEMBL2658779 | 0.72 | QPCT (0.56) | QPCTNSD2POLBGRK2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164085-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-12-06 | — | — | WO | disclosed |
| US-7538222-B2 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| US-7476682-B2 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080051429-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | ACADIA PHARMACEUTICALS INC. | 2008-02-28 | — | — | US | disclosed |
| US-7253186-B2 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS, INC. | 2007-08-07 | — | — | US | disclosed |
| US-20060199818-A1 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS INC. | 2006-09-07 | — | — | US | disclosed |
| US-20060094758-A1 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS, INC. | 2006-05-04 | — | — | US | disclosed |
| US-20040106600-A1 | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| EP-0056577-B1 | TRIAZOLYL-COUMARIN DERIVATIVES, THEIR PREPARATION AND USE AS OPTICAL BRIGHTENING AGENTS SCINTILLATORS AND DYESTUFFS FOR LASERS | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4426530-A | Triazolylcoumarin compounds, and their preparation and use as optical brighteners, scintillators and laser dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |
| EP-0056577-A1 | Triazolyl-coumarin derivatives, their preparation and use as optical brightening agents scintillators and dyestuffs for lasers | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106600-A1 | N-substituted piperidine derivatives as serotonin receptor agents | HTR1A, HTR5A, HTR1B | QPCT 1852/4885NSD2 1451/4885POLB 2313/4885 |
| US-20060094758-A1 | N-substituted piperidine derivatives as serotonin receptor agents | HTR1A, HTR5A, HTR1B | QPCT 1767/4885NSD2 1378/4885POLB 2265/4885 |
| US-20080051429-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | HTR4, HTR3B, HTR2A | QPCT 2836/4885NSD2 331/4885POLB 4145/4885 |
| US-20060199818-A1 | N-substituted piperidine derivatives as serotonin receptor agents | HTR1A, HTR5A, HTR1B | QPCT 1767/4885NSD2 1378/4885POLB 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.