Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.40 |
| ▸ | MMP9 | P14780 | 11/20 | 0.40 |
| ▸ | MMP1 | P03956 | 9/20 | 0.40 |
| ▸ | MMP3 | P08254 | 8/20 | 0.40 |
| ▸ | MMP7 | P09237 | 5/20 | 0.40 |
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791331 | 0.91 | MMP2 (0.40) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6789471 | 0.89 | HDAC6 (0.41) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6795508 | 0.82 | MMP9 (0.40) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL6788683 | 0.79 | MMP2 (0.40) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6790325 | 0.78 | GAA (0.38) | MMP2MMP9MMP1MMP7MMP13 | |
| SCHEMBL6783195 | 0.71 | MMP2 (0.40) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6789040 | 0.71 | GAA (0.42) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7215410 | 0.69 | MMP7 (0.46) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7513829 | 0.68 | MMP2 (0.67) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7212024 | 0.67 | HDAC6 (0.37) | MMP2MMP9MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765003-B1 | ANTICARCINOGENIC, ANTITUMOR, AND ANTIMETASTASIS AGENTS; RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, MULTIPLE SCLEROSIS, STROKE, ARTERIOSCLEROSIS, | PHARMACIA ITALIA, SPA (IT) | 2004-07-20 | — | — | US | disclosed |