Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408887 | 0.81 | NAMPT (0.67) | NAMPTLMNAGAACA12CA1 | |
| SCHEMBL901614 | 0.80 | CA12 (0.73) | NAMPTLMNAGAACA12CA1 | |
| SCHEMBL29356619 | 0.79 | ALDH1A1 (0.77) | NAMPTGAACA1CA2CA9 | |
| SCHEMBL6270935 | 0.79 | ALDH1A1 (0.77) | NAMPTGAACA1CA2CA9 | |
| SCHEMBL27888928 | 0.79 | NAMPT (1.00) | NAMPTLMNAGAAKMT2AALDH1A1 | |
| SCHEMBL7274134 | 0.77 | NPC1 (0.85) | LMNAGAACA1CA2CA9 | |
| SCHEMBL8099685 | 0.77 | CA1 (0.73) | LMNAGAACA12CA1CA2 | |
| SCHEMBL10359474 | 0.77 | CA12 (0.73) | NAMPTGAACA12CA1CA2 | |
| SCHEMBL2224069 | 0.77 | CA12 (0.73) | GAACA12CA1CA2CA9 | |
| SCHEMBL7265002 | 0.77 | CA12 (0.73) | NAMPTLMNAGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784173-B2 | ANTIPROLIFERATIVE AGENTS; ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. | 2004-08-31 | — | — | US | claimed |