Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627288 | 0.80 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 | |
| SCHEMBL354383 | 0.75 | GABRA5 (0.54) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL3938906 | 0.74 | GABRA5 (0.53) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 | |
| SCHEMBL10447417 | 0.71 | GABRA5 (0.34) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 | |
| SCHEMBL958545 | 0.69 | — | — | |
| SCHEMBL222254 | 0.69 | HSD17B10 (0.64) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 | |
| SCHEMBL9627283 | 0.69 | GABRA5 (0.45) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 | |
| SCHEMBL7071564 | 0.69 | ITGB1 (0.46) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL7071663 | 0.69 | ITGB1 (0.46) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL10440125 | 0.69 | GABRA5 (0.50) | GABRA5GABRB2HSD17B10ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087787-A1 | Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-06 | — | — | US | disclosed |
| EP-1347970-A1 | NOVEL THIOESTER DERIVATIVES OF THIAZOLYL ACETIC ACID AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN COMPOUNDS | Orchid Chemicals and Pharmaceuticals Limited (IN) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002053563-A1 | NOVEL THIOESTER DERIVATIVES OF THIAZOLYL ACETIC ACID AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN COMPOUNDS | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2002-07-11 | — | — | WO | disclosed |
| US-6388070-B1 | CHEMICAL INTERMEDIATE | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087787-A1 | Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds | ACOT7, ACACA, COASY | GABRA5 2914/4885GABRB2 3811/4885HSD17B10 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.