Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34467599 | 0.86 | SNCA (0.55) | SNCAALDH1A1PGRCA12CA1 | |
| SCHEMBL13461776 | 0.86 | SNCA (0.55) | SNCAALDH1A1PGRCA12CA1 | |
| SCHEMBL31191629 | 0.79 | ALOX5 (0.59) | SNCAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL21628231 | 0.79 | ALOX5 (0.59) | SNCAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL21753467 | 0.73 | KMT2A (0.43) | SNCAALDH1A1CA12CA1CA2 | |
| SCHEMBL21628199 | 0.72 | MAOB (0.47) | SNCAALDH1A1CA12CA9KDM4E | |
| SCHEMBL21628222 | 0.72 | SNCA (0.63) | SNCAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29636494 | 0.72 | SNCA (0.63) | SNCAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7658287 | 0.71 | ALDH1A1 (0.47) | SNCAALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL13135833 | 0.70 | CA2 (0.46) | SNCAALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116435-A1 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | US | disclosed |