Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654059 | 0.81 | MAOA (0.65) | MAOAMAOBCYP1A2ELANEPARP1 | |
| SCHEMBL11052646 | 0.78 | ALDH1A1 (0.61) | MAOACYP1A2ALDH1A1BACE1POLB | |
| SCHEMBL841604 | 0.78 | POLB (0.46) | MAOAMAOBCYP1A2GPR3ALDH1A1 | |
| SCHEMBL6791707 | 0.78 | MAOA (0.61) | MAOAMAOBCYP1A2GPR3ELANE | |
| SCHEMBL902174 | 0.78 | MAOA (0.61) | MAOAMAOBCYP1A2ELANEALDH1A1 | |
| SCHEMBL455949 | 0.77 | MAOA (1.00) | MAOAMAOBGPR3ALDH1A1POLB | |
| SCHEMBL17506412 | 0.76 | ELANE (0.43) | ELANEPARP1ACHEDHODH | |
| Hydrochloric Acid SCHEMBL28400797 | 0.75 | MAOA (0.95) | MAOAMAOBGPR3ALDH1A1POLB | |
| SCHEMBL9842688 | 0.75 | DHODH (0.48) | ELANEPARP1ALDH1A1POLBKDM4E | |
| SCHEMBL4645969 | 0.74 | CYP1A2 (0.46) | MAOAMAOBCYP1A2ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503824-A | Acridine derivative, preparation method thereof and application of acridine derivative as anti-angiogenesis drug | UNIV GUANGXI CHINESE MEDICINE | 2016-04-20 | — | — | CN | claimed |
| CN-105399726-A | 2-methyl-9-acridine (p-methylphenyl)-1,2,3-triazole and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | claimed |
| CN-105476992-B | Application of the 2- methoxyl group -9- acridine benzamido thiocarbamides in acetylcholinesterase inhibitor is prepared | 广西中医药大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-105503824-A | Acridine derivative, preparation method thereof and application of acridine derivative as anti-angiogenesis drug | UNIV GUANGXI CHINESE MEDICINE | 2016-04-20 | — | — | CN | disclosed |
| CN-105399726-A | 2-methyl-9-acridine (p-methylphenyl)-1,2,3-triazole and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | disclosed |