Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977387 | 0.81 | KDM1A (0.50) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL30182735 | 0.79 | CYP1A2 (0.66) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL11060901 | 0.79 | CYP1A2 (0.66) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL6791707 | 0.78 | MAOA (0.61) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL12886828 | 0.78 | KDM1A (0.48) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL17060429 | 0.78 | CYP1A2 (0.50) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL1187000 | 0.77 | KDM1A (0.51) | KDM1AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2512737 | 0.77 | KDM4E (0.56) | KDM1AKMT2ARAB9ACYP1A2NQO2 | |
| SCHEMBL1186246 | 0.75 | KDM1A (0.46) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL13271201 | 0.74 | ERN1 (0.55) | KDM1AMEN1KMT2ANPC1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888509-B2 | Chiral 1,8-diarylnaphthalenes, methods of making them, and their use as sensors | GEORGETOWN UNIVERSITY (US) | 2011-02-15 | — | — | US | disclosed |
| US-7888509-B2 | Chiral 1,8-diarylnaphthalenes, methods of making them, and their use as sensors | GEORGETOWN UNIVERSITY (US) | 2011-02-15 | — | — | US | disclosed |
| US-20070276140-A1 | Chiral 1,8-Diarylnaphthalenes, Methods of Making Them, and Their Use as Sensors | GEORGETOWN UNIVERSITY (US) | 2007-11-29 | — | — | US | disclosed |
| WO-2005043124-A2 | CHIRAL 1,8-DIARYLNAPHTHALENES, METHODS OF MAKING THEM, AND THEIR USE AS SENSORS | GEORGETOWN UNIVERSITY (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276140-A1 | Chiral 1,8-Diarylnaphthalenes, Methods of Making Them, and Their Use as Sensors | ALKBH2, ALKBH1, ALG3 | KDM1A 620/4885MEN1 916/4885KMT2A 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.