Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.68 |
| ▸ | GSK3B | P49841 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503791 | 0.81 | GSK3A (0.59) | GSK3AGSK3BALDH1A1MAPTLMNA | |
| SCHEMBL40506 | 0.81 | LMNA (0.61) | ALDH1A1MAPTLMNAHTTMAPK1 | |
| SCHEMBL3318940 | 0.81 | GSK3A (1.00) | GSK3AGSK3BALDH1A1MAPTMEN1 | |
| SCHEMBL30953279 | 0.80 | GSK3A (0.71) | GSK3AGSK3BALDH1A1MEN1GAA | |
| SCHEMBL22234108 | 0.75 | GSK3A (0.55) | GSK3AGSK3BALDH1A1MEN1GAA | |
| SCHEMBL14993193 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHTTMAPK1 | |
| SCHEMBL45682 | 0.73 | KDM4E (0.75) | ALDH1A1MAPTLMNAHTTMAPK1 | |
| SCHEMBL6605903 | 0.73 | GSK3A (0.66) | GSK3AGSK3BMEN1GAAKMT2A | |
| SCHEMBL5182321 | 0.73 | GSK3A (0.66) | GSK3AGSK3BMEN1GAAKMT2A | |
| SCHEMBL3031538 | 0.73 | GSK3A (0.66) | GSK3AGSK3BMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242892-A1 | Method for synthesis of 5-(3-pyridylmethylene-)imidazolidine-2,4-dione | SOLVAY S.A. (BE) | 2004-12-02 | — | — | US | disclosed |