SCHEMBL6792103

SCHEMBL6792103

FCN(c1ccc(F)cc1F)C(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.34
CES1 P23141 2/20 0.34
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
IDO1 P14902 2/20 0.32
AGXT P21549 2/20 0.32
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
ACKR3 P25106 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715917 0.85 CES2 (0.34) CES2CES1KDM4ESMN1; SMN2
SCHEMBL6790311 0.80 SLC6A2 (0.36) DDB1CRBN
SCHEMBL6787475 0.78 SOAT1 (0.38)
SCHEMBL6790671 0.72 LMNA (0.33)
SCHEMBL6798740 0.71 PSEN1 (0.36) KDM4ESMN1; SMN2
SCHEMBL2434424 0.71 ALDH1A1 (0.44) CES2CES1ALDH1A1KDM4EIDO1
SCHEMBL13153354 0.70 RIPK1 (0.38) ALDH1A1KDM4EIDO1AGXTDDB1
SCHEMBL6798566 0.70 PSEN1 (0.30)
SCHEMBL5716196 0.69 PSEN1 (0.34)
SCHEMBL6793616 0.69 SOAT1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed