SCHEMBL6792178

SCHEMBL6792178

O=C(Nc1ccc(NCCc2ccccn2)cc1)c1ccccc1-c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
RAB9A P51151 5/20 0.49
NPC1 O15118 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KCNK3 O14649 1/20 0.49
KCNA3 P22001 1/20 0.49
KCNA5 P22460 1/20 0.49
GAA P10253 3/20 0.48
KDM4E B2RXH2 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GPR55 Q9Y2T6 1/20 0.48
POLB P06746 1/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
GLA P06280 1/20 0.47
F2 P00734 1/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6792821 0.90 GAA (0.48) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6796259 0.89 NPC1 (0.50) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6795010 0.89 RAB9A (0.55) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6791511 0.88 HTT (0.57) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6796673 0.88 HTT (0.59) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6789216 0.88 SMN1; SMN2 (0.48) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6793336 0.87 RAB9A (0.65) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6789227 0.87 LMNA (0.50) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6793719 0.87 SMO (0.49) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6792973 0.87 NPC1 (0.47) MAPTMEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MAPT 4795/4885MEN1 2426/4885KMT2A 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.