SCHEMBL6792697

SCHEMBL6792697

CC(C)(C)OC(=O)Nc1cccc(CCN(C(=O)OC(C)(C)C)c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MTTP P55157 12/20 0.45
APOB P04114 9/20 0.45
SMO Q99835 1/20 0.43
RXFP1 Q9HBX9 1/20 0.41
UGCG Q16739 1/20 0.40
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6800939 0.92 GAA (0.42) SMORXFP1GAAKDM4E
SCHEMBL6800937 0.91 BCL2 (0.37) MTTPAPOBRXFP1GAA
SCHEMBL6796042 0.90 MTTP (0.36) MTTPAPOBUGCGGAASMN1; SMN2
SCHEMBL6793746 0.87 SMO (0.53) MTTPAPOBSMO
SCHEMBL6795504 0.87 MTTP (0.42) MTTPAPOBSMORXFP1
SCHEMBL6793653 0.85 POLB (0.38) MTTPSMOGAA
SCHEMBL7085681 0.85 MTTP (0.47) MTTPAPOBSMORXFP1UGCG
SCHEMBL6490168 0.85 RXFP1 (0.35) MTTPAPOBSMORXFP1
SCHEMBL6794786 0.85 POLB (0.38) MTTPGAA
SCHEMBL6787835 0.85 MTTP (0.47) MTTPAPOBSMORXFP1UGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885APOB 1/4885SMO 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.