SCHEMBL6793653

SCHEMBL6793653

Cc1ccc(-c2ccccc2C(=O)Nc2ccc(N(CCc3cccc(NC(=O)OC(C)(C)C)n3)C(=O)O)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.37
MTTP P55157 2/20 0.37
AGTR1 P30556 1/20 0.37
AGTR2 P50052 1/20 0.37
SMO Q99835 2/20 0.36
CHRNB2 P17787 2/20 0.36
CHRNB4 P30926 2/20 0.36
CHRNA3 P32297 2/20 0.36
CHRNA4 P43681 2/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6793443 0.92 MTTP (0.39) POLBGAAALDH1A1KMT2AMTTP
SCHEMBL6788433 0.92 GAA (0.49) POLBGAAALDH1A1KMT2AMTTP
SCHEMBL6800939 0.90 GAA (0.42) POLBGAAL3MBTL1ALDH1A1SMO
SCHEMBL6794499 0.87 CYP3A4 (0.40) POLBGAAL3MBTL1ALDH1A1KMT2A
SCHEMBL6800937 0.87 BCL2 (0.37) POLBGAAMTTPCHRNB2CHRNB4
SCHEMBL6796042 0.86 MTTP (0.36) POLBGAAALDH1A1KMT2AMTTP
SCHEMBL6647849 0.85 ALDH1A1 (0.36) GAAL3MBTL1ALDH1A1NPC1RAB9A
SCHEMBL6792697 0.85 MTTP (0.45) GAAMTTPSMO
SCHEMBL6796543 0.85 AVPR2 (0.38) POLBGAAL3MBTL1KMT2AMTTP
SCHEMBL6787323 0.84 POLB (0.42) POLBGAAL3MBTL1KMT2ACHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 POLB 1470/4885GAA 977/4885L3MBTL1 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.