SCHEMBL6793045

SCHEMBL6793045

O=CN(CCc1cc([N+](=O)[O-])ccn1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNC P24863 1/20 0.41
CDK8 P49336 1/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 6/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CRHBP P24387 1/20 0.40
ATM Q13315 1/20 0.40
CRHR2 Q13324 1/20 0.40
TLR9 Q9NR96 1/20 0.40
PKM P14618 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
MAPT P10636 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6793043 0.81 POLB (0.56) POLBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL6503516 0.79 ASIC3 (0.37) POLBALDH1A1L3MBTL1MAPTLMNA
SCHEMBL6792836 0.77 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AL3MBTL1CRHBP
SCHEMBL6227384 0.77 CYP1A2 (0.49) POLBALDH1A1MAPTCYP1A2CYP3A4
SCHEMBL6792835 0.73 POLB (0.53) POLBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL6252749 0.73 POLB (0.50) POLBALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL6489441 0.73 F2 (0.44) CCNCCDK8POLBALDH1A1MEN1
SCHEMBL4603302 0.71 CCNC (0.49) CCNCCDK8POLBALDH1A1MEN1
SCHEMBL27586516 0.70 CCNC (0.42) CCNCCDK8POLBALDH1A1L3MBTL1
SCHEMBL694426 0.70 POLB (0.43) POLBALDH1A1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 CCNC 4282/4885CDK8 4794/4885POLB 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.