Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339181 | 0.83 | ELANE (0.53) | ALDH1A1HPGDMAPTRAB9AELANE | |
| SCHEMBL7291293 | 0.81 | PREP (0.45) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL8831777 | 0.81 | MAPT (0.61) | ALDH1A1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3519634 | 0.79 | KDM4E (0.31) | CES2CES1HTTKDM4ELMNA | |
| SCHEMBL7902130 | 0.79 | GLRA1 (0.31) | CES2CES1 | |
| SCHEMBL6307030 | 0.79 | KMT2A (0.39) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL7543816 | 0.78 | CA1 (0.64) | ALDH1A1MAPTRAB9ACA1CA2 | |
| SCHEMBL7912420 | 0.77 | CES2 (0.46) | ALDH1A1CES2CES1RAB9APARP1 | |
| SCHEMBL4763549 | 0.76 | CA1 (0.39) | ALDH1A1CA1CA2KMT2AMAPK1 | |
| SCHEMBL9339629 | 0.76 | ELANE (0.61) | ALDH1A1HPGDMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-0598756-B1 | ESTER COMPOSITION | SHELL INT RESEARCH (NL) | 1996-06-05 | — | — | EP | disclosed |
| US-5332858-A | Esterification with active phenolic ether and chloroformyl group and active phenol | SHELL OIL COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0598756-A1 | ESTER COMPOSITION. | SHELL INT RESEARCH (NL) | 1994-06-01 | — | — | EP | disclosed |
| US-5211877-A | Crosslinked resins | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
| WO-1993002038-A1 | ESTER COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1993-02-04 | — | — | WO | disclosed |