SCHEMBL9339181

SCHEMBL9339181

C[Si](C)(C)Oc1ccc(C(=O)c2ccc(O[Si](C)(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.53
KMT2A Q03164 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
LMNA P02545 2/20 0.48
RXFP1 Q9HBX9 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
MAPK1 P28482 1/20 0.48
RAB9A P51151 1/20 0.48
HPGD P15428 1/20 0.48
ALDH1A1 P00352 2/20 0.46
STS P08842 1/20 0.45
GAA P10253 1/20 0.44
SRD5A2 P31213 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9339629 0.92 ELANE (0.61) ELANEKMT2AMEN1MAPTRAB9A
SCHEMBL7688488 0.90 LMNA (0.65) ELANEKMT2ANPSR1LMNARXFP1
SCHEMBL10676086 0.87 SRD5A2 (0.66) ELANERAB9AALDH1A1SRD5A2
SCHEMBL8831777 0.84 MAPT (0.61) KMT2ANPSR1LMNAMAPTRAB9A
SCHEMBL6793622 0.83 ALDH1A1 (0.39) ELANEKMT2ANPSR1LMNAMAPT
SCHEMBL7543816 0.81 CA1 (0.64) KMT2AMEN1MAPTRAB9AALDH1A1
SCHEMBL4763549 0.80 CA1 (0.39) KMT2AMEN1MAPK1ALDH1A1
SCHEMBL2500559 0.79 ELANE (0.52) ELANEKMT2ANPSR1LMNARXFP1
SCHEMBL7539404 0.77 CA12 (0.59) KMT2ANPSR1LMNAMEN1RAB9A
SCHEMBL7754386 0.76 MAPT (0.38) ELANELMNAMAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442068-B1 Benzophenone derivatives and polymers containing phenolic hydroxyl groups BAYER AG (DE) 1994-06-08 EP disclosed
EP-0442068-A2 Benzophenone derivatives and polymers containing phenolic hydroxyl groups BAYER AG (DE) 1991-08-21 EP disclosed