Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902130 | 0.96 | GLRA1 (0.31) | GLRA1CES2CES1 | |
| SCHEMBL7912420 | 0.81 | CES2 (0.46) | KDM4ELMNACES2CES1 | |
| SCHEMBL29831305 | 0.81 | CA12 (0.40) | KDM4EGAA | |
| SCHEMBL5343627 | 0.81 | PLA2G2A (0.46) | KDM4ELMNAPLA2G2A | |
| SCHEMBL14556880 | 0.80 | KDM4E (0.33) | KDM4ELMNAGAA | |
| SCHEMBL6793622 | 0.79 | ALDH1A1 (0.39) | KDM4ELMNAHTTCES2CES1 | |
| SCHEMBL7909395 | 0.79 | PLA2G2A (0.34) | KDM4ELMNAHTTGLRA1PLA2G2A | |
| SCHEMBL7909371 | 0.78 | KDM4E (0.33) | KDM4ELMNAGAA | |
| SCHEMBL5712241 | 0.77 | CA12 (0.40) | — | |
| SCHEMBL9517612 | 0.76 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300424-B1 | Hyperbranched polyesters and polyamides | CORNELL RESEARCH FOUNDATION, INC. | 2001-10-09 | — | — | US | claimed |
| EP-0558556-B1 | HYPERBRANCHED POLYESTERS | CORNELL RES FOUNDATION INC (US) | 1997-04-23 | — | — | EP | claimed |
| EP-0558556-A1 | HYPERBRANCHED POLYESTERS AND POLYAMIDES. | CORNELL RES FOUNDATION INC (US) | 1993-09-08 | — | — | EP | claimed |
| WO-1992008749-A1 | HYPERBRANCHED POLYESTERS AND POLYAMIDES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-05-29 | — | — | WO | claimed |
| US-8445024-B2 | Preparations containing hyperbranched polymers | EVONIK DEGUSSA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-7988953-B2 | cosmetic; dendritic polyether; sunscreens | DSM IP ASSETS B.V. (NL) | 2011-08-02 | — | — | US | disclosed |
| US-7988953-B2 | cosmetic; dendritic polyether; sunscreens | DSM IP ASSETS B.V. (NL) | 2011-08-02 | — | — | US | disclosed |
| EP-1940905-B1 | PREPARATIONS CONTAINING HYPERBRANCHED POLYMERS | EVONIK DEGUSSA GMBH (DE) | 2010-08-11 | — | — | EP | disclosed |
| US-20080207871-A1 | Preparations containing hyperbrached polymers | EVONIK DEGUSSA GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1940905-A1 | PREPARATIONS CONTAINING HYPERBRANCHED POLYMERS | Evonik Degussa GmbH (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-20080081025-A1 | Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers | DSM IP ASSETS B.V. (NL) | 2008-04-03 | — | — | US | disclosed |
| US-20080081025-A1 | Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers | DSM IP ASSETS B.V. (NL) | 2008-04-03 | — | — | US | disclosed |
| US-5225522-A | Multiply-branched aliphatic-aromatic polyesters and method for preparing multiply-branched aliphatic-aromatic polyesters | EASTMAN KODAK COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5214122-A | Preparation of multiply-branched cycloalkyl polyesters and multiply-branched cycloalkyl polyesters | EASTMAN KODAK COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1993009162-A1 | HYPERBRANCHED ARAMIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| EP-0541045-A2 | Method for the preparation of multiply-branched aromatic polyesters | EASTMAN KODAK COMPANY (US) | 1993-05-12 | — | — | EP | disclosed |
| US-5196502-A | Method for the preparation of multiply-branched aromatic polyesters | EASTMAN KODAK COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5183862-A | Capped polylactones uses as sustained release drug delivery, dispersants, adhesives, binders | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-02 | — | — | US | disclosed |
| US-5136014-A | Hyperbranched polyesters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| WO-1992008749-A1 | HYPERBRANCHED POLYESTERS AND POLYAMIDES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081025-A1 | Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers | PCNA, MMS19, ERCC4 | KDM4E 2562/4885LMNA 1092/4885HTT 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.