Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981524 | 0.83 | HSP90AA1 (0.43) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL3519634 | 0.81 | KDM4E (0.31) | CES2CES1KDM4ELMNA | |
| SCHEMBL7902130 | 0.81 | GLRA1 (0.31) | CES2CES1 | |
| SCHEMBL29626810 | 0.79 | CES2 (0.71) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL24402 | 0.79 | CES2 (0.71) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL726592 | 0.79 | AKR1C3 (0.62) | CES2CES1PARP1ALDH1A1TSHR | |
| Ethane SCHEMBL27287143 | 0.78 | CES2 (0.69) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL6793622 | 0.77 | ALDH1A1 (0.39) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL10933601 | 0.77 | AKR1C3 (0.60) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL9769197 | 0.77 | CES2 (0.39) | CES2CES1PARP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300424-B1 | Hyperbranched polyesters and polyamides | CORNELL RESEARCH FOUNDATION, INC. | 2001-10-09 | — | — | US | disclosed |
| EP-0558556-B1 | HYPERBRANCHED POLYESTERS | CORNELL RES FOUNDATION INC (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5514764-A | Hyperbranched polyesters and polyamides | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| US-5270402-A | Hyperbranched polyesters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0558556-A1 | HYPERBRANCHED POLYESTERS AND POLYAMIDES. | CORNELL RES FOUNDATION INC (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5183862-A | Capped polylactones uses as sustained release drug delivery, dispersants, adhesives, binders | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-02 | — | — | US | disclosed |
| US-5136014-A | Hyperbranched polyesters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| WO-1992008749-A1 | HYPERBRANCHED POLYESTERS AND POLYAMIDES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-05-29 | — | — | WO | disclosed |