SCHEMBL6794347

SCHEMBL6794347

CC(C)Oc1ccc(-c2ccccc2C(=O)Nc2ccc(N(CCc3ccccn3)C(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MTTP P55157 3/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
SMO Q99835 2/20 0.40
PNLIP P16233 1/20 0.39
LMNA P02545 2/20 0.38
HTT P42858 1/20 0.38
TP53 P04637 2/20 0.38
GPR88 Q9GZN0 2/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
MCL1 Q07820 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
KCNA5 P22460 2/20 0.36
KCNA3 P22001 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6794735 0.92 GAA (0.51) POLBGAASMOLMNAALDH1A1
SCHEMBL6801791 0.91 NPC1 (0.46) POLBGAASMOLMNAHTT
SCHEMBL6792911 0.91 SMO (0.47) POLBGAASMOLMNAHTT
SCHEMBL6795007 0.91 SMO (0.48) POLBGAASMOLMNAHTT
SCHEMBL6793251 0.90 SMO (0.42) POLBGAASMOLMNAHTT
SCHEMBL6793636 0.90 SMO (0.42) POLBGAASMOLMNAHTT
SCHEMBL6799630 0.90 SMO (0.42) POLBGAASMOLMNAHTT
SCHEMBL6791610 0.90 SMO (0.42) POLBGAASMOLMNAHTT
SCHEMBL6795016 0.90 POLB (0.42) POLBGAASMOLMNAHTT
SCHEMBL6792868 0.90 GAA (0.42) POLBGAASMOLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885POLB 1470/4885GAA 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.