Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | APOB | P04114 | 7/20 | 0.53 |
| ▸ | MTTP | P55157 | 6/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155757 | 0.86 | CHRNB2 (0.69) | ABCG2SMN1; SMN2MAPTRXFP1ALDH1A1 | |
| SCHEMBL31393757 | 0.85 | CHRNB2 (0.71) | SMN1; SMN2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL6496388 | 0.84 | ABCG2 (0.56) | ABCG2SMN1; SMN2MAPTRXFP1ALDH1A1 | |
| SCHEMBL6794747 | 0.84 | PTGS1 (0.60) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL6794883 | 0.83 | P2RX1 (0.56) | ABCG2MAPTALDH1A1APOBMTTP | |
| SCHEMBL6801792 | 0.83 | TP53 (0.56) | SMN1; SMN2MAPTALDH1A1HTTMEN1 | |
| SCHEMBL6791178 | 0.83 | PTGS1 (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9APTGS1 | |
| SCHEMBL3892690 | 0.83 | TRPV1 (0.63) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL6800233 | 0.82 | MTTP (0.54) | ABCG2MAPTRXFP1ALDH1A1HTT | |
| SCHEMBL6789828 | 0.81 | PTGS1 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | ABCG2 501/4885SMN1; SMN2 2504/4885MAPT 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.