SCHEMBL6800233

SCHEMBL6800233

Cc1cc([N+](=O)[O-])ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MTTP P55157 5/20 0.54
ALDH1A1 P00352 2/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ABCG2 Q9UNQ0 1/20 0.52
MAPT P10636 2/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
KCNMA1 Q12791 2/20 0.51
RXFP1 Q9HBX9 2/20 0.51
RORC P51449 2/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083424 0.89 KMT2A (0.52) MTTPALDH1A1NPC1RAB9ATDP1
SCHEMBL6792699 0.83 MTTP (0.58) MTTPALDH1A1MAPTKMT2A
SCHEMBL6794433 0.82 ABCG2 (0.70) MTTPALDH1A1NPC1RAB9AABCG2
SCHEMBL6222007 0.82 MTTP (0.61) MTTPALDH1A1
SCHEMBL14031525 0.80 KCNMA1 (0.66) MTTPALDH1A1NPC1RAB9ATDP1
SCHEMBL6261203 0.80 MTTP (0.62) MTTPALDH1A1KMT2A
SCHEMBL6816754 0.79 MAPT (0.71) ALDH1A1NPC1RAB9ATDP1MAPT
SCHEMBL24460395 0.77 KCNMA1 (0.78) ALDH1A1NPC1RAB9ATDP1MAPT
SCHEMBL1548208 0.76 KMT2A (0.68) ALDH1A1NPC1RAB9ATDP1MAPT
SCHEMBL24460413 0.75 RORC (0.65) ALDH1A1NPC1RAB9ATDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885ALDH1A1 1427/4885NPC1 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.