Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 11/20 | 0.59 |
| ▸ | CA9 | Q16790 | 10/20 | 0.59 |
| ▸ | CA1 | P00915 | 9/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | STS | P08842 | 7/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31519277 | 0.79 | TSHR (0.69) | KDM4EHPGDTSHRHSD17B10CYP19A1 | |
| SCHEMBL27545525 | 0.77 | KDM4E (0.75) | KDM4EHPGDTSHRHSD17B10CYP19A1 | |
| SCHEMBL3475619 | 0.76 | KDM4E (1.00) | KDM4EHPGDTSHRHSD17B10CYP19A1 | |
| SCHEMBL7454758 | 0.76 | CA2 (0.58) | CA2CA9CA1CA12STS | |
| SCHEMBL6797084 | 0.76 | CA1 (0.67) | CA2CA9CA1CA12STS | |
| SCHEMBL28873028 | 0.74 | KDM4E (0.75) | KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL6799239 | 0.74 | STS (0.61) | CA2CA9CA1CA12STS | |
| SCHEMBL4667728 | 0.72 | STS (0.68) | CA2CA9CA1CA12STS | |
| SCHEMBL6799582 | 0.69 | STS (0.63) | CA2CA9CA1CA12STS | |
| SCHEMBL6801523 | 0.68 | CA2 (0.66) | KDM4EHPGDHSD17B10CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |