Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.67 |
| ▸ | CA2 | P00918 | 7/20 | 0.67 |
| ▸ | CA9 | Q16790 | 5/20 | 0.67 |
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.54 |
| ▸ | STS | P08842 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799239 | 0.88 | STS (0.61) | CA1CA2CA9CA12STS | |
| SCHEMBL9451286 | 0.82 | CA2 (1.00) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL6801523 | 0.81 | CA2 (0.66) | CA1CA2CA9CA12STS | |
| SCHEMBL7454758 | 0.81 | CA2 (0.58) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL5992317 | 0.80 | LOXL2 (0.63) | CA1CA2CA12CYP19A1CACNA1B | |
| SCHEMBL10078294 | 0.80 | LOXL2 (0.63) | CA1CA2CA12CYP19A1CACNA1B | |
| SCHEMBL5993780 | 0.78 | MAPT (0.64) | CA1CA2CA9CA12CACNA1B | |
| SCHEMBL4492272 | 0.78 | MAPT (0.64) | CA1CA2CA9CA12CACNA1B | |
| SCHEMBL4665450 | 0.77 | CA2 (0.89) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL6799583 | 0.77 | CA1 (0.68) | CA1CA2CA9CA12STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |