SCHEMBL6795137

SCHEMBL6795137

CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc(NC(=O)c2ccccc2Nc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 17/20 0.52
EGFR P00533 2/20 0.44
KDR P35968 2/20 0.44
ABL1 P00519 1/20 0.44
CSF1R P07333 1/20 0.44
PDGFRB P09619 1/20 0.44
KIT P10721 1/20 0.44
FLT1 P17948 1/20 0.44
FLT4 P35916 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6795046 0.90 RXFP1 (0.58) RXFP1EGFRKDRABL1CSF1R
SCHEMBL6794345 0.86 RXFP1 (0.58) RXFP1EGFRKDRABL1CSF1R
SCHEMBL6793746 0.83 SMO (0.53)
SCHEMBL6791003 0.81 RXFP1 (0.65) RXFP1EGFRKDRABL1CSF1R
SCHEMBL6801997 0.80 MEN1 (0.41) KDR
SCHEMBL6645324 0.80 HTT (0.45)
SCHEMBL6795007 0.79 SMO (0.48)
SCHEMBL6648453 0.79 ALDH1A1 (0.38)
SCHEMBL6788159 0.78 SMO (0.43) KDR
SCHEMBL6787460 0.78 SMO (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 RXFP1 1420/4885EGFR 2619/4885KDR 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.