Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345507 | 0.78 | HRH2 (0.64) | HTR2AHRH2 | |
| SCHEMBL6995543 | 0.75 | SLC6A4 (0.42) | HTR1ASLC6A4BCHEACHESIGMAR1 | |
| SCHEMBL5349323 | 0.72 | HRH2 (0.65) | HTR2AHRH2 | |
| SCHEMBL8555729 | 0.71 | HTR1A (0.64) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| SCHEMBL8557415 | 0.71 | HTR1A (0.64) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| SCHEMBL8559489 | 0.70 | HTR1A (0.60) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| SCHEMBL8558340 | 0.70 | HTR1A (0.60) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| Oxalic Acid SCHEMBL9030775 | 0.70 | SLC6A4 (0.60) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| SCHEMBL5341311 | 0.69 | MTNR1A (0.67) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9031667 | 0.68 | SLC6A4 (0.61) | HTR1ASLC6A4DRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116471-A1 | Indolylpiperidine derivatives as antihistaminic aand antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2004-06-17 | — | — | US | disclosed |