Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991457 | 0.85 | HTR1D (0.46) | HTR2A | |
| SCHEMBL6988593 | 0.79 | HTR1D (0.39) | HTR1AHSD11B1MTNR1AMTNR1B | |
| SCHEMBL6795165 | 0.75 | HTR1A (0.44) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL6992269 | 0.74 | HRH2 (0.54) | HTR2AACHE | |
| SCHEMBL5341487 | 0.70 | HRH2 (0.52) | HTR2A | |
| Oxalic Acid SCHEMBL9030775 | 0.68 | SLC6A4 (0.60) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8555729 | 0.66 | HTR1A (0.64) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8557415 | 0.66 | HTR1A (0.64) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL5341311 | 0.66 | MTNR1A (0.67) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL16801572 | 0.66 | MTNR1A (0.64) | SLC6A4HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330453-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002036589-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2002-05-10 | — | — | WO | disclosed |