Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 11/20 | 0.60 |
| ▸ | HTR1A | P08908 | 10/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | HTR7 | P34969 | 6/20 | 0.58 |
| ▸ | HTR6 | P50406 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9048417 | 0.89 | SLC6A4 (0.55) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9031667 | 0.89 | SLC6A4 (0.61) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9030116 | 0.87 | SLC6A4 (0.63) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Oxalic Acid SCHEMBL9046836 | 0.85 | SLC6A4 (0.51) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Oxalic Acid SCHEMBL9049150 | 0.85 | SLC6A4 (0.51) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9029293 | 0.83 | ADRA1D (0.60) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL25758273 | 0.81 | SLC6A4 (0.66) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8557416 | 0.81 | HTR1A (0.65) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8555335 | 0.80 | HTR1A (0.67) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL5341311 | 0.80 | MTNR1A (0.67) | SLC6A4HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714894-A1 | 3-(1,2,3,6-tetrahydro-(1-alkylenearyl)-4-pyridinyl)- and 3-(1-alkylenearyl)-4-piperidinyl-1h-indoles: new 5-HT1f agonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |