Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6791080 | 0.98 | GAA (0.56) | GAALMNAPKMMAPTHTT | |
| SCHEMBL6795429 | 0.84 | GRIN1 (0.59) | GAALMNAPKMMAPTHTT | |
| Hydrochloric Acid SCHEMBL6791084 | 0.83 | GRIN1 (0.58) | GAALMNAPKMMAPTHTT | |
| SCHEMBL230024 | 0.83 | GAA (0.78) | GAALMNAPKMMAPTHTT | |
| SCHEMBL9540475 | 0.83 | GAA (0.58) | GAAPKMMAPTTSHRGRIN1 | |
| SCHEMBL6887750 | 0.81 | GAA (0.73) | GAALMNAPKMMAPTHTT | |
| SCHEMBL9533110 | 0.78 | TDP1 (0.41) | GAALMNAPKMMAPTHTT | |
| Iodomethane SCHEMBL27491515 | 0.78 | GAA (0.70) | GAALMNAPKMDDAH1POLB | |
| SCHEMBL4066028 | 0.77 | KDM4E (0.40) | GAALMNAPKMMAPTHTT | |
| SCHEMBL28125053 | 0.77 | ACHE (0.39) | GAALMNAPKMMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004066999-A1 | COMPOSITIONS CONTAINING 2, 2’ -METHYLENEBISBENZIMIDAZOLE DERIVATIVES FOR TREATING ISCHEMIA-RELATED NEURONAL DAMAGE | ELAN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |
| US-20040072862-A1 | Compositions for treating ischemia-related neuronal damage | ELAN PHARMACEUTICALS, INC. | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072862-A1 | Compositions for treating ischemia-related neuronal damage | CASP3, NLN, AIFM1 | GAA 779/4885LMNA 488/4885PKM 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.