SCHEMBL6795548

SCHEMBL6795548

CCc1ccc(-c2ccccc2C(=O)Nc2ccc(NC(=O)Cc3csc(N)n3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 3/20 0.51
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
CYP2D6 P10635 1/20 0.47
SLC6A4 P31645 1/20 0.47
KCNH2 Q12809 1/20 0.47
CACNA1C Q13936 1/20 0.47
SCN5A Q14524 1/20 0.47
RAB9A P51151 7/20 0.46
NPC1 O15118 6/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
CTPS1 P17812 1/20 0.46
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
STAT1 P42224 3/20 0.44
KDM4E B2RXH2 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6796525 0.89 MEN1 (0.49) ADRB3MEN1KMT2ACYP2D6SLC6A4
SCHEMBL6905219 0.87 TP53 (0.46) ADRB3MEN1KMT2ARAB9ANPC1
SCHEMBL6794206 0.86 LMNA (0.60) ADRB3MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL6796213 0.85 CTPS1 (0.49) ADRB3MEN1KMT2ACYP2D6RAB9A
SCHEMBL6794781 0.82 RAB9A (0.46) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL6795340 0.81 RAB9A (0.53) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL23132710 0.79 CTPS1 (0.64) ADRB3MEN1KMT2ACYP2D6SLC6A4
SCHEMBL6793972 0.79 RAB9A (0.59) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL6794628 0.77 PTGS1 (0.48) MAPTSMN1; SMN2KDM4ELMNAHTT
SCHEMBL6793046 0.77 NPC1 (0.47) MEN1KMT2ARAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 ADRB3 135/4885MEN1 2426/4885KMT2A 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.