Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 8/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796674 | 0.89 | DRD2 (0.63) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL6794572 | 0.87 | DRD2 (0.59) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL6795833 | 0.85 | DRD2 (0.62) | DRD2HTR2AHTR1ADRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7081164 | 0.84 | DRD2 (0.61) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL27585792 | 0.84 | HTR2A (0.63) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL7215989 | 0.83 | DRD2 (0.55) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL7214528 | 0.77 | DRD2 (0.62) | DRD2HTR2AHTR1ADRD3NOTUM | |
| SCHEMBL11839176 | 0.75 | DRD2 (0.57) | DRD2HTR2AHTR1ANOTUMHTR7 | |
| SCHEMBL7219432 | 0.75 | DRD2 (0.68) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL21485228 | 0.75 | DRD2 (1.00) | DRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044007-A1 | Indoline derivatives | H. LUNDBECK A/S (DK) | 2004-03-04 | — | — | US | claimed |
| US-20040044007-A1 | Indoline derivatives | H. LUNDBECK A/S (DK) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044007-A1 | Indoline derivatives | CNR1, GRIN2C, HTR3C | DRD2 43/4885HTR2A 117/4885HTR1A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.