Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795568 | 0.87 | DRD2 (0.60) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL6796674 | 0.85 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL6795833 | 0.85 | DRD2 (0.62) | DRD2HTR1AHTR2ADRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7081164 | 0.84 | DRD2 (0.61) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL6792592 | 0.83 | DRD2 (0.52) | DRD2HTR1AHTR2ADRD4NOTUM | |
| SCHEMBL27585792 | 0.83 | HTR2A (0.63) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL7215989 | 0.82 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL6789252 | 0.78 | HTR1A (0.47) | DRD2HTR1AHTR2ANOTUMMAPT | |
| SCHEMBL7214607 | 0.77 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD4AVPR1A | |
| SCHEMBL7220723 | 0.77 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044007-A1 | Indoline derivatives | H. LUNDBECK A/S (DK) | 2004-03-04 | — | — | US | claimed |
| US-20040044007-A1 | Indoline derivatives | H. LUNDBECK A/S (DK) | 2004-03-04 | — | — | US | disclosed |
| EP-1345921-A1 | 3-INDOLINE DERIVATIVES USEFUL IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGIC DISORDERS | H. Lundbeck A/S (DK) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051833-A1 | 3-INDOLINE DERIVATIVES USEFUL IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGIC DISORDERS | H. LUNDBECK A/S (DK) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044007-A1 | Indoline derivatives | CNR1, GRIN2C, HTR3C | DRD2 43/4885HTR1A 7/4885HTR2A 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.