Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7081164 | 0.99 | DRD2 (0.61) | DRD2HTR1AHTR2ANOTUMSLC6A2 | |
| SCHEMBL6796674 | 0.90 | DRD2 (0.63) | DRD2HTR1AHTR2ANOTUMSLC6A2 | |
| SCHEMBL6795568 | 0.85 | DRD2 (0.60) | DRD2HTR1AHTR2ANOTUMDRD4 | |
| SCHEMBL6794572 | 0.85 | DRD2 (0.59) | DRD2HTR1AHTR2ANOTUMSLC6A4 | |
| SCHEMBL7215989 | 0.81 | DRD2 (0.55) | DRD2HTR1AHTR2ANOTUMDRD4 | |
| SCHEMBL11839176 | 0.77 | DRD2 (0.57) | DRD2HTR1AHTR2ANOTUMALDH1A1 | |
| SCHEMBL7214528 | 0.77 | DRD2 (0.62) | DRD2HTR1AHTR2ANOTUMDRD3 | |
| SCHEMBL21485228 | 0.77 | DRD2 (1.00) | DRD2HTR1AHTR2A | |
| SCHEMBL7219432 | 0.77 | DRD2 (0.68) | DRD2HTR1AHTR2ADRD4DRD3 | |
| Hydrochloric Acid SCHEMBL21485258 | 0.76 | DRD2 (0.98) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1491223-A | 3-indoline derivatives useful for the treatment of psychiatric and neurological disorders | H��¡�±�������˾ | 2004-04-21 | — | — | CN | claimed |
| US-20040044007-A1 | Indoline derivatives | H. LUNDBECK A/S (DK) | 2004-03-04 | — | — | US | claimed |
| CN-1491223-A | 3-indoline derivatives useful for the treatment of psychiatric and neurological disorders | H��¡�±�������˾ | 2004-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044007-A1 | Indoline derivatives | CNR1, GRIN2C, HTR3C | DRD2 43/4885HTR1A 7/4885HTR2A 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.