Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | SMAD2 | Q15796 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623201 | 0.72 | MEN1 (0.46) | AOC3CYP19A1KDM4ELMNAMAPT | |
| SCHEMBL6620807 | 0.71 | ALDH1A1 (0.48) | CYP2C9KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL6622341 | 0.70 | POLB (0.40) | KDM4EMAPTTDP1TGFBR1BMPR1A | |
| SCHEMBL9261384 | 0.67 | GRM5 (0.48) | CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL16772203 | 0.65 | MAPT (0.59) | CYP3A4CYP19A1KDM4ELMNAMAPT | |
| SCHEMBL5547117 | 0.62 | KDM4E (0.56) | METCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL7467666 | 0.62 | LTA4H (0.51) | — | |
| SCHEMBL12266908 | 0.62 | CYP2E1 (0.57) | METCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4737237 | 0.61 | TP53 (0.45) | CYP3A4LMNAALDH1A1 | |
| SCHEMBL2095228 | 0.61 | CYP2E1 (0.49) | METCYP2E1CYP3A4CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266842-A1 | Thiazolyl substituted triazoles as alk5 inhibitors | GASTER LARAMIE MARY | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266842-A1 | Thiazolyl substituted triazoles as alk5 inhibitors | CBR3, CBR1, ALK | AOC3 233/4885MET 183/4885CYP2E1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.